Recombinant Mouse Nectin-4 (C-Fc)
| Code | Size | Price |
|---|
| PKSM041375-10ug | 10ug | £177.00 |
Quantity:
| PKSM041375-50ug | 50ug | £280.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
Nectin-4
Accession:
Q8R007
Activity:
Immobilized Recombinant Mouse Nectin-4 (C-6His)(Cat#PKSM041376) at 10ug/ml (100 ul/well) can bind Recombinant Mouse Nectin-4 (C-Fc)(Cat#PKSM041375). The ED50 of PKSM041375 is 0.75 ug/ml.
Background:
Nectin-4(PVRL4)isatypeItransmembraneglycoproteinwhichbelongstothenectinfamilyofIgsuperfamilyproteins.ItcontainstwoIg-likeC2-typedomainsandoneIg-likeV-typedomain.PVRL4seemstobeinvolvedincelladhesionthroughtrans-homophilicand-heterophilicinteractions,thelatterincludingspecificallyinteractionswithnectin-1.Itdoesnotactasreceptorforalpha-herpesvirusentryintocells.Itispredominantlyexpressedinplacenta,theembryoandbreastcarcinoma.Butitisnotdetectedinnormalbreastepithelium.Thesolubleformisproducedbyproteolyticcleavageatthecellsurface(shedding),probablybyADAM17.Mutationsinthisgenearethecauseofectodermaldysplasia-syndactylysyndrometype 1, an autosomal recessive disorder.
Calculated MW:
61.4 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Fc
ObservedMW:
75-85 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Gly31-Ser349
Target Synonym:
PVRL4;Nectin-4;Ig superfamily receptor LNIR;Poliovirus receptor-related protein 4;PRR4;LNIR
UNIProt ID:
Q8R007