Recombinant Human GAS6 (C-6His)
| Code | Size | Price |
|---|
| PKSH033928-10ug | 10ug | £308.00 |
Quantity:
| PKSH033928-50ug | 50ug | £770.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Further Information
Abbreviation:
GAS6
Accession:
Q14393
Activity:
Immobilized Human AXL-His at 10ug/ml (100 ul/well) can bind Human GAS6-His : Biotinylated by NHS-biotin prior to testing. The ED50 of Recombinant Human GAS6-His is 0.04466 ug/ml.
Background:
GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Calculated MW:
72.7 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of PBS, 10% Glycerol, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
80-90 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ala31-Ala678
Target Synonym:
AXLLG;AXLLGAXL stimulatory factor;AXSFAXL receptor tyrosine kinase ligand;Gas6;GAS-6;growth arrest-specific 6;growth arrest-specific protein 6
UNIProt ID:
Q14393