Recombinant Human CD59 (C-6His)
| Code | Size | Price |
|---|
| PKSH034028-10ug | 10ug | £160.00 |
Quantity:
| PKSH034028-50ug | 50ug | £327.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
CD59
Accession:
P13987
Background:
CD59, also known as membrane attack complex inhibition factor (MACIF), Protectin, 1F5 antigen, HRF-20 and MIRL, is an approximately 20 kDa GPI anchored glycoprotein that is an important regulator of the complement system in blood. CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 was first identified as a regulator of the terminal pathway of complement. It acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
Calculated MW:
9.8 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
15-20 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Leu26-Asn102
Target Synonym:
1F5 antigen;1F5;20 kDa homologous restriction factor;CD59 antigen;CD59 glycoprotein;CD59;HRF20;HRF-20;MACIF;MAC-IP;MIC11;MIC11MSK21;MIN1;MIN2;MIN3;MIRL;p18-20;16.3A5;EL32;FLJ38134;FLJ92039;G344
UNIProt ID:
P13987