Recombinant Human Tumor-associated Calcium Signal Transducer 2/TROP-2 (248AA, C-6His)
| Code | Size | Price |
|---|
| PKSH033991-10ug | 10ug | £112.00 |
Quantity:
| PKSH033991-50ug | 50ug | £181.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
TROP-2
Accession:
P09758
Activity:
Immobilized Human TROP-2-His at 2ug/ml (100 ul/well) can bind Anti-Human TROP-2 mAb. The ED50 of Anti-Human TROP-2 mAb is 13.03 ng/ml.
Background:
Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
Calculated MW:
28.9 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
40-50 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
His27-Thr274
Target Synonym:
Tumor-associated calcium signal transducer 2;Membrane component chromosome 1 surface marker 1;Cell surface glycoprotein Trop-2;TACSTD2;TROP2
UNIProt ID:
P09758