Angiotensinogen Polyclonal Antibody

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Elabscience
Product Code: E-AB-40478
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-40478-20uL20uL£120.00
Quantity:
E-AB-40478-60uL60uL£160.00
Quantity:
E-AB-40478-120uL120uL£230.00
Quantity:
E-AB-40478-200uL200uL£331.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Mouse kidney using Angiotensinogen Polycloanl Antibody at dilution of 1:200.
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Immunohistochemistry of paraffin-embedded Mouse kidney using Angiotensinogen Polycloanl Antibody at dilution of 1:200.

Documents

Further Information

Abbreviation:
Angiotensinogen
Background:
Angiotensinogen is a precursor of angiotensin II (Ang II),is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product,angiotensin I,is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension,and can cause renal tubular dysgenesis,a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation,and inflammatory bowel disease.
Buffer:
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Calculated MW:
52 kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:2000-1:5000 IHC 1:100-1:300
Immunogen:
Recombinant Mouse Angiotensinogen protein
ObservedMW:
52 kDa
Purification method:
Antigen Affinity Purification
Target Synonym:
Aangiotensinogen (serpin peptidase inhibitor clade A member 8); AGT; AI265500; Alpha 1 antiproteinase antitrypsin; Ang; Ang I; Ang II; Ang III; AngII; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-3; Angiotensinogen (PAT); Angiotensinogen; ANGT; ANHU; ANRT; AT-2; AT-II; Des-Asp[1]-angiotensin II; PAT; Pre angiotensinogen; Serine (or cysteine) proteinase inhibitor; Serpin A8; Serpin peptidase inhibitor clade A member 8; SERPINA8
UNIProt ID:
P11859