PDE3A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-67264-60uL | 60uL | £210.00 |
Quantity:
| E-AB-67264-120uL | 120uL | £291.00 |
Quantity:
| E-AB-67264-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PDE3A
Background:
This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100 IF 1:50-1:100
Immunogen:
Recombinant fusion protein of human PDE3A (NP_000912.3).
Purification method:
Affinity purification
Target Synonym:
HTNB;CGI-PDE;CGI-PDE A;CGI-PDE-A;PDE3A
UNIProt ID:
Q14432