HSD17B1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-65790-60uL | 60uL | £210.00 |
Quantity:
| E-AB-65790-120uL | 120uL | £291.00 |
Quantity:
| E-AB-65790-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
HSD17B1
Background:
Hydroxysteroid (17-beta) dehydrogenase 1 catalyzes the final step in the formation of estradiol and testosterone from estrone and androstenedione, respectively. Ovarian granulosa cells and breast tissue both express HSD17B1. Other tissues that express HSD17B1 include testis, placenta, uterus, prostate and adipose tissue. HSD17B1 functions as a homodimer and prefers NADP(H) over NAD(H) for oxidation and reduction. The gene encoding human HSD17B1 maps to chromosome 17q12-q21. The importance of HSD17B1 to estradiol production suggests the specific inhibition of HSD17B1 may aid in breast cancer therapy.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human HSD17B1 (NP_000404.2).
Purification method:
Affinity purification
Target Synonym:
HSD17B1;17-beta-HSD;20-alpha-HSD;E2DH;EDH17B2;EDHB17;HSD17;SDR28C1
UNIProt ID:
P14061