ITGB3BP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-66360-60uL | 60uL | £210.00 |
Quantity:
| E-AB-66360-120uL | 120uL | £291.00 |
Quantity:
| E-AB-66360-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ITGB3BP
Background:
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human ITGB3BP (NP_055103.3).
Purification method:
Affinity purification
Target Synonym:
ITGB3BP;CENP-R;CENPR;HSU37139;NRIF3;TAP20
UNIProt ID:
Q13352