EGLN1/EGLN2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-65763-60uL | 60uL | £210.00 |
Quantity:
| E-AB-65763-120uL | 120uL | £291.00 |
Quantity:
| E-AB-65763-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
EGLN1/EGLN2
Background:
The proteins encoded by EGLN1/EGLN2 gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
36kDa/43kDa/46kDa/40kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human EGLN1/EGLN2
ObservedMW:
44kDa
Purification method:
Affinity purification
Target Synonym:
EGLN1/EGLN2
UNIProt ID:
Q9GZT9,Q96KS0