DMBT1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40467-20uL | 20uL | £120.00 |
Quantity:
| E-AB-40467-60uL | 60uL | £160.00 |
Quantity:
| E-AB-40467-120uL | 120uL | £230.00 |
Quantity:
| E-AB-40467-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
DMBT1
Background:
Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system.
Buffer:
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Concentration:
0.71mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:200-1:500
Immunogen:
Recombinant Human Deleted in malignant brain tumors 1 protein
Purification method:
Antigen Affinity Purification
Target Synonym:
Apactin; CRP; Crpd; DBMT1; Deleted in malignant brain tumors 1 protein; DMBT1; DMBT1 prototype precursor; Ebnerin; FLJ61058; Glycoprotein 300; Glycoprotein 340; GP340; Gp340 variant protein; GP340; Hensin; MGC164738; Muclin; p80; Pancrin; SAG; Salivary agglutinin; Surfactant pulmonary associated D binding protein; Vomeroglandin
UNIProt ID:
Q9UGM3