SNW1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-66311-60uL | 60uL | £210.00 |
Quantity:
| E-AB-66311-120uL | 120uL | £291.00 |
Quantity:
| E-AB-66311-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
SNW1
Background:
This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
61kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human SNW1 (NP_036377.1).
ObservedMW:
70kDa/75kDa
Purification method:
Affinity purification
Target Synonym:
SNW1;Bx42;NCOA-62;PRPF45;Prp45;SKIIP;SKIP;FUN20;SKIP1
UNIProt ID:
Q13573