CYP11A1 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-67057-60uL | 60uL | £210.00 |
Quantity:
E-AB-67057-120uL | 120uL | £291.00 |
Quantity:
E-AB-67057-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
CYP11A1
Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
42kDa/60kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IHC 1:20-1:50 IF 1:20-1:50
Immunogen:
Recombinant fusion protein of human CYP11A1 (NP_000772.2).
ObservedMW:
50kDa
Purification method:
Affinity purification
Target Synonym:
CYP11A1;CYP11A;CYPXIA1;P450SCC
UNIProt ID:
P05108