SKIL Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-67710-60uL | 60uL | £210.00 |
Quantity:
| E-AB-67710-120uL | 120uL | £291.00 |
Quantity:
| E-AB-67710-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
SKIL
Background:
The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
44kDa/46kDa/71kDa/74kDa/76kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human SKIL
ObservedMW:
75KDa
Purification method:
Affinity purification
Target Synonym:
SKIL;SNO;SnoA;SnoI;SnoN
UNIProt ID:
P12757