NTRK1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-66502-60uL | 60uL | £210.00 |
Quantity:
| E-AB-66502-120uL | 120uL | £291.00 |
Quantity:
| E-AB-66502-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
NTRK1
Background:
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
77kDa/83kDa/86kDa/87kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IHC 1:50-1:200
Immunogen:
A synthetic peptide of human NTRK1 (NP_002520.2).
ObservedMW:
140kDa
Purification method:
Affinity purification
Target Synonym:
NTRK1;MTC;TRK;TRK1;TRKA;Trk-A;p140-TrkA
UNIProt ID:
P04629