FGG Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40412-20uL | 20uL | £120.00 |
Quantity:
| E-AB-40412-60uL | 60uL | £160.00 |
Quantity:
| E-AB-40412-120uL | 120uL | £230.00 |
Quantity:
| E-AB-40412-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
FGG
Background:
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms.
Buffer:
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Calculated MW:
49 kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:3000 IHC 1:100-1:300
Immunogen:
Recombinant Mouse Fibrinogen gamma chain protein
ObservedMW:
49 kDa
Purification method:
Antigen Affinity Purification
Target Synonym:
FGG; Fibrinogen gamma chain; Fibrinogen gamma polypeptide
UNIProt ID:
Q8VCM7