NPM1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40477-20uL | 20uL | £120.00 |
Quantity:
| E-AB-40477-60uL | 60uL | £160.00 |
Quantity:
| E-AB-40477-120uL | 120uL | £230.00 |
Quantity:
| E-AB-40477-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
NPM1
Background:
Nucleophosmin (NPM1,B23) is a putative ribosome assembly factor with a high affinity for peptides containing nuclear localization signals (NLSs). The transport of proteins across the nuclear envelope is a selective,multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates,dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Several cytosolic and nuclear proteins that are central to this process have been identified. The 38 kDa nuclear protein nucleophosmin is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis.
Buffer:
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Calculated MW:
32 kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:10000-1:20000 IHC 1:200-1:500
Immunogen:
Recombinant Mouse Nucleophosmin protein
ObservedMW:
37 kDa
Purification method:
Antigen Affinity Purification
Target Synonym:
B23; MGC104254; NO38; NPM; NPM; NPM1; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Nucleophosmin (nucleolar phosphoprotein B23 numatrin); Nucleophosmin; nucleophosmin nucleoplasmin family member 1; Nucleophosmin/nucleoplasmin family member 1; Numatrin
UNIProt ID:
Q61937