UNG Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-66016-60uL | 60uL | £210.00 |
Quantity:
| E-AB-66016-120uL | 120uL | £291.00 |
Quantity:
| E-AB-66016-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
UNG
Background:
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
33kDa/34kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IF 1:50-1:100
Immunogen:
A synthetic peptide of human UNG (NP_550433.1).
ObservedMW:
38kDa
Purification method:
Affinity purification
Target Synonym:
UNG;DGU;HIGM4;HIGM5;UDG;UNG1;UNG15;UNG2
UNIProt ID:
P13051
References
- https://pubs.acs.org/doi/abs/10.1021/acs.biochem.2c00344