TPM3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-65867-60uL | 60uL | £210.00 |
Quantity:
| E-AB-65867-120uL | 120uL | £291.00 |
Quantity:
| E-AB-65867-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
TPM3
Background:
This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
18kDa/28kDa/29kDa/32kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human TPM3 (NP_689476.2).
ObservedMW:
38kDa
Purification method:
Affinity purification
Target Synonym:
TPM3;CAPM1;CFTD;HEL-189;HEL-S-82p;NEM1;OK/SW-cl.5;TM-5;TM3;TM30;TM30nm;TM5;TPMsk3;TRK;hscp30
UNIProt ID:
P06753