(KO Validated) SEC61B Polyclonal Antibody

Contact us
Elabscience
Product Code: E-AB-66577
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-66577-60uL60uL£224.00
Quantity:
E-AB-66577-120uL120uL£317.00
Quantity:
E-AB-66577-200uL200uL£465.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 1
Western blot analysis of extracts from normal (control) and SEC61B knockout (KO) 293T cells using SEC61B Polyclonal Antibody at dilution of 1:1000.
❮❯

Western blot analysis of extracts from normal (control) and SEC61B knockout (KO) 293T cells using SEC61B Polyclonal Antibody at dilution of 1:1000.

Documents

Further Information

Abbreviation:
SEC61B
Background:
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
9kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IF 1:50-1:200
Immunogen:
A synthetic peptide of human SEC61B (NP_006799.1).
ObservedMW:
12kDa
Purification method:
Affinity purification
Target Synonym:
SEC61B
UNIProt ID:
P60468