PGC1 alpha Polyclonal Antibody

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Elabscience
Product Code: E-AB-65852
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-65852-60uL60uL£210.00
Quantity:
E-AB-65852-120uL120uL£291.00
Quantity:
E-AB-65852-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines using PGC1 alpha Polyclonal Antibody at dilution of 1:1000.
2 / 2
Immunofluorescence analysis of HeLa cells using PGC1 alpha Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Western blot analysis of extracts of various cell lines using PGC1 alpha Polyclonal Antibody at dilution of 1:1000.
Immunofluorescence analysis of HeLa cells using PGC1 alpha Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

Documents

Further Information

Abbreviation:
PGC1 alpha
Background:
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
14kDa/30kDa/31kDa/33kDa/77kDa/89kDa/91kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IF 1:50-1:200
Immunogen:
A synthetic peptide of human PGC1 alpha (NP_037393.1).
ObservedMW:
110kDa
Purification method:
Affinity purification
Target Synonym:
PPARGC1A;LEM6;PGC-1(alpha);PGC-1alpha;PGC-1v;PGC1;PGC1A;PPARGC1;PPARG coactivator 1 alpha;PGC1 alpha
UNIProt ID:
Q9UBK2

References

  • https://www.sciencedirect.com/science/article/pii/S0024320522009584
  • https://onlinelibrary.wiley.com/doi/abs/10.1096/fj.201901510RR
  • https://www.sciencedirect.com/science/article/pii/S0024320522003496