MKL1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-66247-60uL | 60uL | £210.00 |
Quantity:
| E-AB-66247-120uL | 120uL | £291.00 |
Quantity:
| E-AB-66247-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
MKL1
Background:
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
98kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IF 1:50-1:100
Immunogen:
Recombinant fusion protein of human MKL1 (NP_065882.1).
ObservedMW:
150kDa
Purification method:
Affinity purification
Target Synonym:
MKL1;BSAC;MAL;MRTF-A
UNIProt ID:
Q969V6