BBC3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-67059-60uL | 60uL | £210.00 |
Quantity:
| E-AB-67059-120uL | 120uL | £291.00 |
Quantity:
| E-AB-67059-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
BBC3
Background:
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
10kDa/14kDa/20kDa/26kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IF 1:50-1:100
Immunogen:
A synthetic peptide of human BBC3 (NP_001120713.1).
ObservedMW:
20kDa
Purification method:
Affinity purification
Target Synonym:
BBC3;JFY-1;JFY1;PUMA
UNIProt ID:
Q96PG8,Q9BXH1