WWOX Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-65948-60uL | 60uL | £210.00 |
Quantity:
| E-AB-65948-120uL | 120uL | £291.00 |
Quantity:
| E-AB-65948-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
WWOX
Background:
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
4kDa/21kDa/23kDa/26kDa/35kDa/41kDa/46kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000
Immunogen:
Recombinant fusion protein of human WWOX (NP_057457.1).
ObservedMW:
46kDa
Purification method:
Affinity purification
Target Synonym:
WWOX;D16S432E;EIEE28;FOR;FRA16D;HHCMA56;PRO0128;SCAR12;SDR41C1;WOX1
UNIProt ID:
Q9NZC7