TBP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40487-30uL | 30uL | £125.00 |
Quantity:
| E-AB-40487-60uL | 60uL | £146.00 |
Quantity:
| E-AB-40487-120uL | 120uL | £196.00 |
Quantity:
| E-AB-40487-200uL | 200uL | £216.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
TBP
Background:
The TATA binding protein (TBP) is a transcription factor that binds specifically to a DNA sequence TATA box. This DNA sequence is found about 25-30 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP,along with a variety of TBP-associated factors,make up the TFIID,a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitation complex that binds DNA in a sequence-specific manner,it helps position RNA polymerase II over the transcription start site of the gene. However,it is estimated that only 10-20% of human promoters have TATA boxes. Therefore,TBP is probably not the only protein involved in positioning RNA polymerase II. This antibody detects human TBP (~40 kDa) and mouse/rat Tbp (~35 kDa).
Buffer:
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Calculated MW:
38 kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:4000-1:6000
Immunogen:
Synthetic peptide of Human TATA-box-binding protein
ObservedMW:
38 kDa
Purification method:
Antigen Affinity Purification
Target Synonym:
GTF2D; GTF2D1; HDL4; SCA17; TATA binding factor; TATA box binding protein; TATA box factor; TATA sequence binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-box factor; TATA-box-binding protein; TBP; TBP; TFIID; Transcription initiation factor TFIID TBP subunit
UNIProt ID:
P20226