FREM1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-66871-60uL | 60uL | £210.00 |
Quantity:
| E-AB-66871-120uL | 120uL | £291.00 |
Quantity:
| E-AB-66871-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
FREM1
Background:
This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
25kDa/42kDa/80kDa/244kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human FREM1 (NP_659403.4).
ObservedMW:
72kDa
Purification method:
Affinity purification
Target Synonym:
FREM1;BNAR;C9orf143;C9orf145;C9orf154;MOTA;TILRR;TRIGNO2
UNIProt ID:
Q5H8C1