TNFRSF11A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-65990-60uL | 60uL | £210.00 |
Quantity:
| E-AB-65990-120uL | 120uL | £291.00 |
Quantity:
| E-AB-65990-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunofluorescence (IF)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
TNFRSF11A
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IF 1:50-1:100
Immunogen:
Recombinant fusion protein of human TNFRSF11A (NP_003830.1).
Purification method:
Affinity purification
Target Synonym:
TNFRSF11A;CD265;FEO;LOH18CR1;ODFR;OFE;OPTB7;OSTS;PDB2;RANK;TRANCER
UNIProt ID:
Q9Y6Q6