SIRT1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-67101-60uL | 60uL | £210.00 |
Quantity:
| E-AB-67101-120uL | 120uL | £291.00 |
Quantity:
| E-AB-67101-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
![Immunofluorescence analysis of HeLa cells using [KO Validated] SIRT1 Polyclonal Antibody at dilution of 1:250 (40x lens). Blue: DAPI for nuclear staining.](/images/blue_dot.png)
Further Information
Abbreviation:
SIRT1
Background:
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
61kDa/81kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:200
Immunogen:
A synthetic peptide of human SIRT1
ObservedMW:
120kDa
Purification method:
Affinity purification
Target Synonym:
SIR2;SIR2L1;SIR2alpha;SIRT1;sirtuin 1
UNIProt ID:
Q96EB6