OTUB1 Polyclonal Antibody

Elabscience
Product Code: E-AB-65829
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-65829-60uL60uL£210.00
Quantity:
E-AB-65829-120uL120uL£291.00
Quantity:
E-AB-65829-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Immunofluorescence (IF)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunofluorescence analysis of U2OS cells using OTUB1 Polyclonal Antibody at dilution of  1:100. Blue: DAPI for nuclear staining.

Immunofluorescence analysis of U2OS cells using OTUB1 Polyclonal Antibody at dilution of  1:100. Blue: DAPI for nuclear staining.

Documents

Further Information

Abbreviation:
OTUB1
Background:
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human OTUB1 (NP_060140.2).
Purification method:
Affinity purification
Target Synonym:
OTUB1;HSPC263;OTB1;OTU1
UNIProt ID:
Q96FW1