APC Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-67493-60uL | 60uL | £210.00 |
Quantity:
| E-AB-67493-120uL | 120uL | £291.00 |
Quantity:
| E-AB-67493-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
APC
Background:
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human APC (NP_000029.2).
Purification method:
Affinity purification
Target Synonym:
APC;BTPS2;DP2;DP2.5;DP3;GS;PPP1R46
UNIProt ID:
P25054