PLAUR Polyclonal Antibody
Code | Size | Price |
---|
E-AB-40370-20uL | 20uL | £120.00 |
Quantity:
E-AB-40370-60uL | 60uL | £160.00 |
Quantity:
E-AB-40370-120uL | 120uL | £230.00 |
Quantity:
E-AB-40370-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
PLAUR
Background:
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
Buffer:
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Concentration:
0.85mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Recombinant Human Urokinase plasminogen activator surface receptor protein
Purification method:
Antigen Affinity Purification
Target Synonym:
CD 87;CD87;CD87 antigen;MO 3;MO3;Monocyte activation antigen Mo3;Plasminogen activator receptor urokinase;Plasminogen activator urokinase receptor;PLAUR;U PAR;u plasminogen activator receptor;U-PAR;u-plasminogen activator receptor form 2;UPA receptor;uPAR;UPAR;Urinary plasminogen activator receptor;URKR;Urokinase plasminogen activator receptor;Urokinase plasminogen activator surface receptor;urokinase-type plasminogen activator (uPA) receptor
UNIProt ID:
Q03405