FUBP1 Polyclonal Antibody

Elabscience
Product Code: E-AB-65928
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-65928-60uL60uL£210.00
Quantity:
E-AB-65928-120uL120uL£291.00
Quantity:
E-AB-65928-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of HepG2 cells using FUBP1 Polyclonal Antibody at dilution of 1:1000.

Western blot analysis of extracts of HepG2 cells using FUBP1 Polyclonal Antibody at dilution of 1:1000.

Documents

Further Information

Abbreviation:
FUBP1
Background:
The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the regulation of c-myc in undifferentiated cells. This protein contains three domains, an amphipathic helix N-terminal domain, a DNA-binding central domain, and a C-terminal transactivation domain that contains three tyrosine-rich motifs. The N-terminal domain is thought to repress the activity of the C-terminal domain. This protein is also thought to bind RNA, and contains 3'-5' helicase activity with in vitro activity on both DNA-DNA and RNA-RNA duplexes. Aberrant expression of this gene has been found in malignant tissues, and this gene is important to neural system and lung development. Binding of this protein to viral RNA is thought to play a role in several viral diseases, including hepatitis C and hand, foot and mouth disease. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
67kDa/68kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human FUBP1 (NP_003893.2).
ObservedMW:
74kDa
Purification method:
Affinity purification
Target Synonym:
FUBP1;FBP;FUBP;hDH V;hDHV
UNIProt ID:
Q96AE4