TIMP1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-66160-60uL | 60uL | £210.00 |
Quantity:
| E-AB-66160-120uL | 120uL | £291.00 |
Quantity:
| E-AB-66160-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
TIMP1
Background:
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
23kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human TIMP1
ObservedMW:
26KDa
Purification method:
Affinity purification
Target Synonym:
TIMP1;CLGI;EPA;EPO;HCI;TIMP;TIMP-1
UNIProt ID:
P01033