RCAN1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-67645-60uL | 60uL | £210.00 |
Quantity:
| E-AB-67645-120uL | 120uL | £291.00 |
Quantity:
| E-AB-67645-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
RCAN1
Background:
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
13kDa/19kDa/22kDa/28kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human RCAN1
ObservedMW:
31kDa
Purification method:
Affinity purification
Target Synonym:
RCAN1;ADAPT78;CSP1;DSC1;DSCR1;MCIP1;RCN1
UNIProt ID:
P53805