Rb Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-67411-60uL | 60uL | £210.00 |
Quantity:
| E-AB-67411-120uL | 120uL | £291.00 |
Quantity:
| E-AB-67411-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Immunofluorescence (IF)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
Rb
Background:
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IF 1:50-1:200
Immunogen:
A synthetic peptide of human Rb (NP_000312.2).
Purification method:
Affinity purification
Target Synonym:
OSRC;PPP1R130;RB;p105-Rb;pRb;pp110;RB1;Rb
UNIProt ID:
P06400