TAZ Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-66586-60uL | 60uL | £210.00 |
Quantity:
| E-AB-66586-120uL | 120uL | £291.00 |
Quantity:
| E-AB-66586-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Immunofluorescence (IF)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
TAZ
Background:
TAZ, also referred as WWTR1, is a transcriptional co-activator with a PDZ-binding motif that is regulated by its interaction with 14-3-3 protein. TAZ is expressed in many primary tumors, such as breast cancer, thyroid carcinoma, colorectal cancer, and glioma. TAZ has been reported to be one of the nuclear effectors of Hippo-related pathways that regulate organ size control, cancer stem cell (CSC) properties, and epithelial?mesenchymal transition (EMT). TAZ has been defined for its role in the nucleus, where it functions directly as a transcriptional regulator by interacting with several nuclear factors as Runx2/Cbfa1, NHERF-2, TEF-1, TBX5, PAX3, PAX8 and TTF-1.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IF 1:50-1:200
Immunogen:
A synthetic peptide of human TAZ (NP_056287.1).
Purification method:
Affinity purification
Target Synonym:
BTK;AGMX1;AT;ATK;BPK;IMD1;PSCTK1;XLA;Bruton tyrosine kinase;TAZ;WWTR1
UNIProt ID:
Q9GZV5
References
- https://www.nature.com/articles/s41590-022-01166-6