ALKBH4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-67916-60uL | 60uL | £210.00 |
Quantity:
| E-AB-67916-120uL | 120uL | £291.00 |
Quantity:
| E-AB-67916-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ALKBH4
Background:
Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1, thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. In addition to proteins, also demethylates DNA: specifically demethylates DNA methylated on the 6th position of adenine (N(6-methyladenosine DNA, thereby regulating Polycomb silencing (By similarity.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
4kDa/33kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human ALKBH4
ObservedMW:
36kDa
Purification method:
Affinity purification
Target Synonym:
ALKBH4;ABH4
UNIProt ID:
Q9NXW9