RUNX1T1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-67119-60uL | 60uL | £210.00 |
Quantity:
| E-AB-67119-120uL | 120uL | £291.00 |
Quantity:
| E-AB-67119-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
RUNX1T1
Background:
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
44kDa/48kDa/63kDa/64kDa/67kDa/68kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000
Immunogen:
Recombinant fusion protein of human RUNX1T1 (NP_783554.1).
ObservedMW:
67kDa
Purification method:
Affinity purification
Target Synonym:
RUNX1T1;AML1-MTG8;AML1T1;CBFA2T1;CDR;ETO;MTG8;ZMYND2
UNIProt ID:
Q06455