RTN3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-66432-60uL | 60uL | £210.00 |
Quantity:
| E-AB-66432-120uL | 120uL | £291.00 |
Quantity:
| E-AB-66432-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
RTN3
Background:
This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
23kDa/25kDa/26kDa/27kDa/100kDa/110kDa/112kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human RTN3 (NP_006045.1).
ObservedMW:
26kDa
Purification method:
Affinity purification
Target Synonym:
RTN3;ASYIP;HAP;NSPL2;NSPLII;RTN3-A1
UNIProt ID:
O95197