Elab Fluor® Red 780 Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1]
| Code | Size | Price |
|---|
| E-AB-F1112S-50Tests | 50Tests | £113.00 |
Quantity:
| E-AB-F1112S-100Tests | 100Tests | £134.00 |
Quantity:
| E-AB-F1112S-100Testsx2 | 100Testsx2 | £180.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: Rat IgM, κ
Antibody Clone: RA3.3A 1/6.1
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
Ice packs
Storage:
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Further Information
Abbreviation:
CD45R/B220
Background:
CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
5 uL/Test
Conjugation:
Elab Fluor® Red 780
GeneID:
192,645,788
Target Synonym:
B220;
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.