Elabscience

Elab Fluor® Red 780 Anti-Mouse F4/80 Antibody[CI:A3-1]

Product Code:
 
E-AB-F0995S
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2b, κ
Antibody Clone:
 
CI:A3-1
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
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C57BL/6 murine abdominal macrophages elicited by starch broth are stained with FITC Anti-Mouse/Human CD11b Antibody and Elab Fluor® Red 780 Anti-Mouse F4/80 Antibody (Left). Macrophages are stained with FITC Anti-Mouse/Human CD11b Antibody and Elab Fluor® Red 780 Rat IgG2b, κ Isotype Control (Right).
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C57BL/6 murine abdominal macrophages elicited by starch broth are stained with FITC Anti-Mouse/Human CD11b Antibody and Elab Fluor® Red 780 Anti-Mouse F4/80 Antibody (Left). Macrophages are stained with FITC Anti-Mouse/Human CD11b Antibody and Elab Fluor® Red 780 Rat IgG2b, κ Isotype Control (Right).

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CodeSizePrice
E-AB-F0995S-50Tests50Tests£109.00
Quantity:
E-AB-F0995S-100Tests100Tests£125.00
Quantity:
E-AB-F0995S-100Testsx2100Testsx2£149.00
Quantity:
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Further Information

Abbreviation:
F4/80
Background:
F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
5 uL/Test
Conjugation:
Elab Fluor® Red 780
GeneID:
13733
Target Synonym:
Adhesion G protein-coupled receptor E1;Adgre1;Cell surface glycoprotein F4/80;EGF-like module receptor 1;Adgre1;Emr1; Gpf480;
UNIProt ID:
Q61549
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

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