Elab Fluor® 647 Anti-Human CD16 Antibody[3G8]
Code | Size | Price |
---|
E-AB-F1236M-20Tests | 20Tests | £137.00 |
Quantity:
E-AB-F1236M-100Tests | 100Tests | £228.00 |
Quantity:
E-AB-F1236M-100Testsx2 | 100Testsx2 | £338.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, κ
Antibody Clone: 3G8
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
Ice packs
Storage:
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Images
Further Information
Abbreviation:
CD16
Background:
CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
5 uL/Test
Conjugation:
Elab Fluor® 647
GeneID:
941
Target Synonym:
FcγRIII;Fc gamma receptor;Fc gamma receptor 3;
UNIProt ID:
P08637;O75015;
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
References
- https://www.frontiersin.org/articles/10.3389/fcimb.2021.785166/full?utm_source=dlvr.it&utm_medium=twitter
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