Purified Anti-Human CD11a Antibody[R7-1]
Code | Size | Price |
---|
E-AB-F1211A-25ug | 25ug | £105.00 |
Quantity:
E-AB-F1211A-100ug | 100ug | £141.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, κ
Antibody Clone: R7-1
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
Ice packs
Storage:
Store at 2-8°C. Do not freeze.
Further Information
Abbreviation:
CD11a
Background:
CD11a is < 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
GeneID:
3683
Target Synonym:
Integrin alpha-L;LFA-1A;CD11A;ITGAL;
UNIProt ID:
P20701
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is < 2.0 ug per 10^6 cells in 100 uL volume or 100 uL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
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