AF/LE Purified Anti-Mouse CD120b Antibody[TR75-54.7]
Code | Size | Price |
---|
E-AB-F10350-50ug | 50ug | £140.00 |
Quantity:
E-AB-F10350-500ug | 500ug | £341.00 |
Quantity:
E-AB-F10350-1mg | 1mg | £475.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Antibody Isotype: Armenian Hamster IgG
Antibody Clone: TR75-54.7
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Blocking
- Flow Cytometry
Shipping:
Ice packs
Storage:
Store at 2-8°C. Do not freeze.
Further Information
Abbreviation:
CD120b/TNFR2
Background:
CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.
Buffer:
0.2 um filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Concentration:
0.5 mg/mL
Conjugation:
None (Purified antibody-Azide Free/Low endotoxin)
GeneID:
21938
Target Synonym:
Tumor necrosis factor receptor superfamily member 1B;Tnfrsf1b;Tumor necrosis factor receptor 2;TNF-R2;TNF-RII;TNFR-II;p75;p80 TNF-alpha receptor;CD120b;
UNIProt ID:
P25119
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is < 0.25 ug per 10^6 cells in 100 uL volume or 100 uL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
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