ATN1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53586-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53586-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53586-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53586-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ATN1
Background:
Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.ATN1 (Atrophin 1) is a Protein Coding gene. Diseases associated with ATN1 include Dentatorubro-Pallidoluysian Atrophy and Spinocerebellar Ataxia 1. GO annotations related to this gene include protein domain specific binding. An important paralog of this gene is RERE.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human ATN1
Purification method:
Antigen affinity purification
Target Synonym:
ATN1;Atrophin1;B37;D12S755E;Dentatorubral-pallidoluysian atrophy protein;DRPLA;HRS;NOD
UNIProt ID:
P54259