YBX1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53542-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53542-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53542-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53542-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
YBX1
Background:
This protein mediates pre-mRNA alternative splicing regulation. It binds to splice sites in pre-mRNA and regulates splice site selection and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It can regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro).
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human YBX1
Purification method:
Antigen affinity purification
Target Synonym:
BP 8;CBF-A;CCAAT binding transcription factor I subunit A;CCAAT-binding transcription factor I subunit A;CSDA2;CSDB;DBPB;DNA binding protein B;DNA-binding protein B;EFI-A;Enhancer factor I subunit A;MDR NF1;MGC104858;MGC110976;MGC117250;NSEP 1;NSEP1;Nuclease sensitive element binding protein 1;Nuclease-sensitive element-binding protein 1;p50;Q15905;Y-box binding protein 1;Y-box transcription factor;Y-box-binding protein 1;YB 1;YB-1;YBOX1;YBX 1;ybx1
UNIProt ID:
P67809