EFNB1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53525-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53525-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53525-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53525-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
EFNB1
Background:
Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human EFNB1
Purification method:
Antigen affinity purification
Target Synonym:
CFND;CFNS;Craniofrontonasal syndrome (craniofrontonasal dysplasia);EFL 3;EFL-3;EFL3;EFNB1;EFNB1;Elk L;ELK ligand;ELK-L;Eph related receptor tyrosine kinase ligand 2;EPH-related receptor tyrosine kinase ligand 2;Ephrin-B1;EPLG2;LERK 2;LERK-2;LERK2;Ligand of eph related kinase 2;MGC8782
UNIProt ID:
P98172