ARHGDIB Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53461-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53461-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53461-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53461-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ARHGDIB
Background:
ARHGDIB,also known as RhoGDI2,is a conserved member of the RhoGDI family and plays an important role in cell migrations. It regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them,and the subsequent binding of GTP to them.
It is mainly in hematopoietic,endothelial,and epithelial cells. It has been linked to tumorigenesis and metastasis. RhoGDI2 expression is downregulated in several cancer types,such as bladder,lung and lymphoma,but is upregulated in prostate and gastric cancer.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
23 kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human ARHGDIB
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
Arhgdib;D4;D4 GDP dissociation inhibitor;GDIA 2;GDIA2;GDID 4;GDID4;GDIR2;GDP dissociation inhibitor D4;LY GDI;Ly-GDI;LYGDI;MGC108926;RAP1GN1;Rho GDI 2;Rho GDI beta;Rho GDI2;Rho GDP dissociation inhibitor (GDI) beta;Rho GDP dissociation inhibitor 2;Rho GDP dissociation inhibitor beta;Rho GDP-dissociation inhibitor 2;Rho-GDI beta;RhoGDI2
UNIProt ID:
P52566