BRI3BP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53455-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53455-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53455-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53455-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
BRI3BP
Background:
BRI3BP (BRI3 binding protein), also known as BNAS1, HCCR-1, I3-binding protein or cervical cancer 1 proto-oncogene-binding protein KG19, is a 251 amino acid multi-pass membrane protein. Though widely expressed, BRI3BP is found at highest levels in brain, kidney and liver where it localizes to the endoplasmic reticulum (ER) and is involved in ER structural dynamics and mitochondrial viability. Possessing pro-apoptotic properties and the ability to potentiate drug-induced apoptosis, BRI3BP overexpression has been shown to enhance caspase-3 and mitochondrial cytochrome c release in etoposide-treated human embryonic kidney 293T cells.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
28 kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human BRI3BP
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
BNAS1;BRI3 binding protein;BRI3-binding protein;BRI3B;Bri3bp;Cervical cancer 1 proto oncogene binding protein KG19;Cervical cancer 1 proto-oncogene-binding protein KG19;cervical cancer oncogene binding protein;HCCR-2;HCCR1;HCCRBP-1;I3 binding protein;I3-binding protein;KG19
UNIProt ID:
Q8WY22