PLA2G16 Polyclonal Antibody

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Elabscience
Product Code: E-AB-53452
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-53452-20uL20uL£125.00
Quantity:
E-AB-53452-60uL60uL£172.00
Quantity:
E-AB-53452-120uL120uL£237.00
Quantity:
E-AB-53452-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PLA2G16 Polyclonal Antibody at dilution of 1:40(?200)
2 / 2
Immunohistochemistry of paraffin-embedded Human tonsil tissue using PLA2G16 Polyclonal Antibody at dilution of 1:40(?200)
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Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PLA2G16 Polyclonal Antibody at dilution of 1:40(?200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using PLA2G16 Polyclonal Antibody at dilution of 1:40(?200)

Documents

Further Information

Abbreviation:
PLA2G16
Background:
Secretory phopholipase A2 (PLA2) enzymes cleave an acyl ester bond in the sn-2 position of glycerophospholipids. These extracellular proteins have a high disulfide bond content, low molecular mass (14 kDa), and require mM levels of Ca2+ for catalysis. They play a crucial role in the generation of arachidonates and eicosanoids, and have a number of biological actions including immunological responses, inflammation, cellular proliferation, vasoconstriction, and bronchioconstriction. Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue (By similarity). N- and O-acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human PLA2G16
Purification method:
Antigen affinity purification
Target Synonym:
Adipose specific phospholipase A2;Adipose specific PLA2;Adipose-specific phospholipase A2;AdPLA;Ca independent phospholipase A1/2;Group XVI phospholipase A1/A2;Group XVI phospholipase A2;H rev 107 protein homolog;H REV107 1;H-rev 107 protein homolog;HRAS like suppressor 1;HRAS like suppressor 3;HRAS-like suppressor 1;HRAS-like suppressor 3;HREV107 1;HREV107 3;HREV107;HREV107-1;HREV107-3;HRSL3;HRSL3;Phospholipase A2 group XVI;Pla2g16;Renal carcinoma antigen NY REN 65 ;Renal carcinoma antigen NY-REN-65
UNIProt ID:
P53816