GZMM Polyclonal Antibody

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Elabscience
Product Code: E-AB-53442
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-53442-20uL20uL£125.00
Quantity:
E-AB-53442-60uL60uL£172.00
Quantity:
E-AB-53442-120uL120uL£237.00
Quantity:
E-AB-53442-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of RAW264.7 cell using GZMM Polyclonal Antibody at dilution of 1:400
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Immunohistochemistry of paraffin-embedded Human brain tissue using GZMM Polyclonal Antibody at dilution of 1:25(?200)
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Western blot analysis of RAW264.7 cell using GZMM Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human brain tissue using GZMM Polyclonal Antibody at dilution of 1:25(?200)

Documents

Further Information

Abbreviation:
GZMM
Background:
GZMM (Granzyme M) is a Protein Coding gene. Diseases associated with GZMM include Adrenal Insufficiency, Congenital, With 46Xy Sex Reversal, Partial Or Complete and Congenital Adrenal Insufficiency. Among its related pathways are Innate Immune System and Granzyme Pathway. GO annotations related to this gene include serine-type endopeptidase activity and endopeptidase activity. An important paralog of this gene is CFD.Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
28 kDa
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human GZMM
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
GRAM;Granzyme M (lymphocyte met ase 1);Granzyme M;GranzymeM;GZM M;Gzmm;HU Met 1;HU-Met-1;LMET 1;LMET1;Lymphocyte met ase 1;MET 1;Met 1 serine protease;Met ase;Met-1 serine protease;Met-ase;MET1;Met1 serine protease;Natural killer cell granular protease
UNIProt ID:
P51124